Type I and type III collagen metabolites in adult osteosarcoma patients
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چکیده
منابع مشابه
Type I and III collagen metabolites as predictors of clinical outcome in epithelial ovarian cancer.
We evaluated the significance of biochemical tumor markers, ie, aminoterminal propeptide of type III procoliagen, trivalently cross-linked COOH-terminal telopeptide of type I collagen (ICTP), aminoterminal propeptide of type I procollagen, and CA 125 in the prediction of ovarian cancer outcome and compared them with several classical indicators of prognosis. The concentrations of biochemical ma...
متن کاملCollagen type I, collagen type III, and versican in vocal fold lamina propria.
OBJECTIVE To analyze the distributions of collagen type I, collagen type III, and versican in the lamina propria of the human vocal fold. DESIGN Cross-sectional analysis of cadaveric vocal folds of adult human larynges. SETTING Academic tertiary referral center. SUBJECTS Larynges harvested at autopsy from 10 adult men and 10 adult women. MAIN OUTCOME MEASURES Immunohistochemical reactio...
متن کاملSustained expression of proteoglycans and collagen type III/type I ratio in a calcified tendinopathy model.
OBJECTIVES Alteration in the composition of extracellular matrix has been suggested as the major factor for the development of tendinopathy and calcified tendinopathy, which has poorer clinical manifestation. This study investigated the changes of major proteoglycans and collagens in a calcified tendinopathy model and correlated the expression with the acquisition of chondrocyte phenotype, ecto...
متن کاملType I and type III collagen mRNA expression in human lung fibroblasts.
The predominant histological features of pulmonary fibrosis are an accumulation of collagen in the alveolar interstitium. and an increase in the number of fibroblasts [ l ] . There is an alteration in collagen production with an increase in Type I collagen relative to Type II. The mechanisms involved in this regulation of collagen production at transcriptional and translational level are poorly...
متن کاملFibrogenesis. III. Posttranscriptional regulation of type I collagen.
There are several independent metabolic steps that determine the level of a protein in eukaryotic cells. The steady-state level of the mRNA encoding the specific protein is determined by rate of transcription, percentage of transcripts that are ultimately processed and transported to the cytoplasm, and half-life of the mRNA in cytoplasm. The amount of protein that accumulates from a particular ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1996
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1996.19